Therapeutic implications of diastolic dysfunction in heart failure.
نویسندگان
چکیده
منابع مشابه
Therapeutic implications of diastolic dysfunction in heart failure.
The idea that diastolic dysfunction may give rise to symptoms of cardiac disease independent of any impairment of systolic function is not new, and was appreciated centuries ago.2 Traditional definitions of heart failure have focused on abnormalities of systolic or pump function ofthe heart, emphasizing the failure of cardiac output to meet the metabolic requirements of the body at peak workloa...
متن کامل[Diastolic dysfunction and diastolic heart failure].
There are frequent clinical Cases in Cardiological practice when cardiac failure develops together with normal systolic function of left ventricle. In these patients after revealing the diastolic dysfunction the heart diastolic failure is diagnosed, but in frequent cases this diagnosis is based on exclusion method. According to Framingham data the number of patients with clinically manifested d...
متن کاملMechanisms of diastolic dysfunction in heart failure.
Abnormalities of diastole are common to most forms of congestive heart failure (HF). Diastolic function is broadly defined as the ability of the heart to fill adequately and at normal pressure to charge the ventricular pump for each subsequent contraction. It is determined by both active and passive processes occurring at the level of the myocyte, extracellular matrix, and left ventricular cham...
متن کاملDiastolic dysfunction and diastolic heart failure: diagnostic, prognostic and therapeutic aspects
Left ventricular (LV) diastolic dysfunction (DD) and diastolic heart failure (HF), that is symptomatic DD, are due to alterations of myocardial diastolic properties. These alterations involve relaxation and/or filling and/or distensibility. Arterial hypertension associated to LV concentric remodelling is the main determinant of DD but several other cardiac diseases, including myocardial ischemi...
متن کاملDifferentiating diastolic dysfunction from classic heart failure
Heart failure (HF) is characterized by an impaired ability of the ventricle to fill with and eject blood commensurate with the metabolic demands and requirements of the body, and has emerged as a major cause of morbidity and mortality in the developed world. Approximately 50% of HF patients have preserved ejection fraction, and lack overt signs of systolic failure, but rather have deficits in v...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1991
ISSN: 0032-5473
DOI: 10.1136/pgmj.67.788.588